Everything about Herpes B Virus totally explained
B Virus(Cercopithecine herpesvirus 1,
herpesvirus simiae, Herpes B virus) is the endemic
simplex virus of
macaques, in which the
virus exhibits
pathogenesis similar to that of
herpes simplex virus in humans. Conversely, when humans are
zoonotically infected with B virus, undiagnosed and untreated patients can present with severe
CNS disease, resulting in permanent neurological dysfunction or death. It is estimated that the
mortality rate for untreated patients is near 80%. The last known fatality occurred when a worker at the
Yerkes National Primate Research Center was infected in
1997. Proper personal protective equipment is essential when working with macaque monkeys, especially those who have tested positive for the virus. Bites, scratches, and exposures to
mucous membranes, including the eye, must be cleansed immediately and samples from the macaque and human should be sent for B virus diagnostic testing as recommended by the B Virus Working Group here:
BVIRUS.pdf
As of 1992, there had been approximately 25 reported cases of Herpes B of which 16 patients died, and at least 20 developed
encephalitis.
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